Research and Review Articles:
Cryo-EM analysis of Ebola virus nucleocapsid-like assembly. STAR Protocol (2022) PMID: 34977676
Wang Y, Binning JM, Pintilie GD, Chiu W, Amarasinghe GK, Leung DW, Su Z.
Structural basis for a species-specific determinant of an SIV Vif protein towards hominid APOBEC3G antagonism. Cell Host and Microbe (2019) PMID: 31830442
Binning JM, Chesarino NM, Emerman M, Gross JD
Conformational flexibility of the HIV Vif protein complex. Biophys J. (2019) PMID: 30961890
Ball KA, Chan LM, Stanley DJ, Tierney E, Thapa S, Ta HM, Burton L, Binning JM, Jacobson MP, Gross JD
Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly. Cell (2018) PMID: 29474922
Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, Gross ML, Leung DW, Chiu W, Amarasinghe GK
Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors. PLoS Pathog. (2018) PMID: 29304101
Binning JM, Smith AM, Hultquist JF, Craik CS, Caretta N, Campbell MG, Burton L, La Greca F, McGregor MJ, Ta HM, Bartholomeeusen K, Peterlin BM, Krogan NJ, Sevillano N, Cheng Y, Gross JD
Making Sense of MultifunctionalProteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription. Annu Rev Virol. (2017) PMID: 28961413
Faust TB, Binning JM, Gross JD, Frankel AD
An intrinsically disordered peptide from ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions. Cell Rep. (2015) PMID: 25865894
Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, Amarasinghe GK.
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep. (2015) PMID: 25981045.
Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ.
In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity. J Mol Biol. (2014) PMID: 24495995
Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito MLM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, Binning JM, Tonelli M, Olson MA, Davey RA, Ready JM, Basler CF, Amarasinghe GK
Development of RNA aptamers targeting Ebola virus VP35. Biochemistry (2013) PMID: 24067086
Binning JM*, Wang T*, Luthra P, Shabman RS, Borek DM, Liu G, Xu W, Leung DW, Basler CF, Amarasinghe GK
An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication. PLoS Pathog. (2013) PMID: 23382680
Shabman RS, Hoenen T, Groseth A, Jabado O, Binning JM, Amarasinghe GK, Feldmann H, Basler CF
Profile of biochemical traits influencing tenderness of muscles from the beef round. Meat Sci. (2012) PMID: 22386323
Anderson MJ, Lonergan SM, Fedler CA, Prusa KJ, Binning JM, Huff-Lonergan E.
Aptamers in virology: Recent advances and challenges. Front Microbiol. (2012) PMID: 22347221
Binning JM, Leung DW, Amarasinghe GK.
Basic residues within the ebolavirus VP35 protein are required for its viral polymerase cofactor function. J Virol. (2010) PMID: 20686031
Prins KC, Binning JM, Shabman RS, Leung DW, Amarasinghe GK, Basler CF.
Wang Y, Binning JM, Pintilie GD, Chiu W, Amarasinghe GK, Leung DW, Su Z.
Structural basis for a species-specific determinant of an SIV Vif protein towards hominid APOBEC3G antagonism. Cell Host and Microbe (2019) PMID: 31830442
Binning JM, Chesarino NM, Emerman M, Gross JD
Conformational flexibility of the HIV Vif protein complex. Biophys J. (2019) PMID: 30961890
Ball KA, Chan LM, Stanley DJ, Tierney E, Thapa S, Ta HM, Burton L, Binning JM, Jacobson MP, Gross JD
Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly. Cell (2018) PMID: 29474922
Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, Gross ML, Leung DW, Chiu W, Amarasinghe GK
Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors. PLoS Pathog. (2018) PMID: 29304101
Binning JM, Smith AM, Hultquist JF, Craik CS, Caretta N, Campbell MG, Burton L, La Greca F, McGregor MJ, Ta HM, Bartholomeeusen K, Peterlin BM, Krogan NJ, Sevillano N, Cheng Y, Gross JD
Making Sense of MultifunctionalProteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription. Annu Rev Virol. (2017) PMID: 28961413
Faust TB, Binning JM, Gross JD, Frankel AD
An intrinsically disordered peptide from ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions. Cell Rep. (2015) PMID: 25865894
Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, Amarasinghe GK.
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep. (2015) PMID: 25981045.
Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ.
In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity. J Mol Biol. (2014) PMID: 24495995
Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito MLM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, Binning JM, Tonelli M, Olson MA, Davey RA, Ready JM, Basler CF, Amarasinghe GK
Development of RNA aptamers targeting Ebola virus VP35. Biochemistry (2013) PMID: 24067086
Binning JM*, Wang T*, Luthra P, Shabman RS, Borek DM, Liu G, Xu W, Leung DW, Basler CF, Amarasinghe GK
An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication. PLoS Pathog. (2013) PMID: 23382680
Shabman RS, Hoenen T, Groseth A, Jabado O, Binning JM, Amarasinghe GK, Feldmann H, Basler CF
Profile of biochemical traits influencing tenderness of muscles from the beef round. Meat Sci. (2012) PMID: 22386323
Anderson MJ, Lonergan SM, Fedler CA, Prusa KJ, Binning JM, Huff-Lonergan E.
Aptamers in virology: Recent advances and challenges. Front Microbiol. (2012) PMID: 22347221
Binning JM, Leung DW, Amarasinghe GK.
Basic residues within the ebolavirus VP35 protein are required for its viral polymerase cofactor function. J Virol. (2010) PMID: 20686031
Prins KC, Binning JM, Shabman RS, Leung DW, Amarasinghe GK, Basler CF.
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